六溴環十二烷 (HBCD) 是被廣泛使用的溴化阻燃劑 (BFR) 之一，通常被添加到各種的消費產品中；然而， 由於其潛在的毒性、在環境中的持久性以及高生物蓄積性，使它被列為持久性有機污染物 (POP)。在本研究中，評估了真菌處理對於去除六溴環十二烷的效果，並測試了三種真菌 (靈芝H菌株、靈芝PT菌株以及牛樟芝) 對於六溴環十二烷的移除能力，同時首次在批次處理實驗中評估了三種不同真菌對於六溴環十二烷的吸收作用。我們的結果顯示，三種真菌菌株都能在1天的處理試驗後，從水溶液中去除大約80%的六溴環十二烷； 然而，在去除反應結束時並未檢測到溴離子。此外，經高壓滅菌的菌絲體 (SG1-H，SG1-PT和SAC) 顯示出約75%的六溴環十二烷去除效果，表明這些真菌物種透過吸收作用去除大部分的六溴環十二烷。這些發現為六溴環十二烷設計可行的生物修復方法提供了有用的資訊。

Hexabromocyclododecane (HBCD) was widely used as one of the brominated flame retardants (BFRs), which were routinely added to various consumer products; however, it has been listed as a persistent organic pollutant (POP) due to its potential toxicity, persistence in the environment and high bioaccumulation characteristics. In this study, the effect of fungal treatment to eliminate HBCD has been evaluated. Three strains of fungi (Ganoderma lucidum strain H, G. lucidum strain PT, and Antrodia cinnamomea) were examined for their HBCD removal abilities. The sorption of HBCD by the three different fungi was first evaluated in batch experiments. Our result shows all the three strains were able to eliminate approximately 80% of HBCD from aqueous solutions after 1 day. However, no bromide ions were measured at the end of the removal reactions. Furthermore, the autoclaved mycelia (SGl-H, SGl-PT, and SAC) show a 75% HBCD elimination, indicating that the fungal species showed most of the removal by sorption. These findings provide useful information to design feasible methods for bioremediation of HBCD.