慢性腎臟病是永久性疾病亦是全球關注的健康議題。本研究目的為探討初期慢性腎臟病患者知識與自我照護行為之相關。採橫斷式相關研究設計，立意取樣在北區某教學醫院共130位初期慢性腎臟病患。問卷含腎臟病知識量表與慢性腎臟病自我照護行為量表。統計採獨立樣本t檢定、單因子變異數及皮爾森積差相關統計。結果顯示疾病知識答對率55.10%，自我照護行為答對率達81.4%。疾病知識與性別(t=2.64, p＜0.01)、年齡(F=7.66, p＜0.001)、教育程度(F=20.74, p＜0.001)、就業(t=4.64, p＜0.001)等呈顯著差異。自我照顧行為與教育程度(F=4.76, p＜0.001)、宗教信仰(F=5.08, p＜0.01)呈顯著差異。疾病知識與自我照顧行(r=0.36, p＜0.01)呈正相關。患者具備正確疾病知識高就越能執行良好的自我照顧行為，提供醫護人員參酌。

Chronic kidney disease is a progressive, permanent and global health concern. Patients learn to take care of themselves to adapt to the disease and reduce medical cost. The purpose of this study is to explore the relationships of knowledge and self-care behaviors in patients with early-stage chronic kidney disease. We applied a cross-sectional and correlation research design. A deliberate sampling of 130 early-stage chronic kidney disease patients at a teaching hospital were recruited. Data were collected by using the chronic kidney disease knowledge scale and the chronic kidney disease self-care behavior scale. Descriptive statistics, independent sample t test, ANOVA and Pearson product correlation were applied to analyze the data. The results showed that the correct response of disease knowledge and self-care behaviors were 55.10% and 81.4% respectively. Disease knowledge has statistical significant difference in gender (t=2.64, p＜0.01), age (F=7.66, p＜0.001), education level (F=20.74, p＜0.001), marital status (F=4.45, p＜0.05), employment status (t=4.64, p＜0.001), and religion belief (F=5.89, p＜0.001). Furthermore, self-care behavior has statistical significant difference in education level (F=4.76, p＜0.001) and religion belief (F=5.08, p＜0.01) . There was a significant positive correlation between disease knowledge and self-care behavior (r = 0.36, p <0.01). Patients with more correct knowledge of the disease can perform better self-care behavior. This research results may have implication for medical staffs to improve the patient's disease knowledge and self-care behaviors.