前言：勞動部於107年1月5日公告「指定長期夜間工作之勞工為雇主應施行特定項目健康檢查之特定對象」，期雇主重視長期夜間工作同仁的健康管理與工作適性。國內外已有許多研究顯示長時間夜班可能導致心臟代謝疾病風險高、肥胖或疲勞…等身心健康問題；北區某半導體廠長期夜間工作同仁約4000人，全廠人數達8000人，為具代表意義本土性資料，研究分析後可作為我國職業衛生政策參考。研究方法：本描述性研究將該廠2020年健檢結果，分為長期夜間工作及非長期夜間工作同仁兩組，將睡眠時數與壓力量表結果以SPSS進行統計分析，探討長期夜間工作與睡眠、壓力疲勞及運動習慣之關聯性。長期夜間工作，依我國職安署公布，分為工作日數及時數兩種。夜間工作指晚上10點至清晨6點間工作。全年度夜間工作時數累積達700小時以上，或每月夜間工作達3小時的日數佔當月工作日1/2，且全年度有6個月以上者。研究結果：蒐集該廠所有同仁2020年健檢資料，有效樣本共8286人。其中夜間工作者3957人(47.8%)，非夜間工作者4329人(52.2%)。結果指出，長期夜間工作同仁比非長期夜間工作同仁並沒有較高壓力承擔，實際分析反而30歲以下夜班工作者疲勞量表疲勞程度略低於非長期夜間工作者；30歲以上同仁則兩組工作者間疲勞程度並沒有顯著差異，即夜班工作與否可能非疲勞的影響因子。另外，夜間工作同仁有較少睡眠時數，達統計意義。

Background and Aims: Potential effected of night shift work is well-known for its correlation with high risk of cardiovascular disease, obesity, and fatigue. The aim of this study was to make a analysis from the annual health check data (March, 2020) of the employees in a North-Taiwan semiconductor company, to evaluate the associations between night shift work and concerning effects on sleep duration and stress. Methods: A total 8286 workers from the semiconductor company were recruited，3957 workers were night-shift employees, and 4329 workers were non-shift employees. A structured self-administered questionnaire (Copenhagen Burnout Inventory, CBI) was employed to collect the participant’ stress effect. Main Outcome Measures: stress measuring personal burnout and work-related burnout from self-administered questionnaire(Copenhagen Burnout Inventory, CBI). Sleep duration was evaluated, as well. Results: For those who were more than 30 years old, the was no difference in stress between the night-shift employees and the non-shift employees; however, for those who were less than 30 years old, the night-shift workers have less stress. However, night shift worker had decreased hours of sleep. Conclusion: Night shift work were likely associated with decreased sleep duration; however, no stress differences were found between night-shift workers and non-shift workers. We recommend that all the companies pay highly attention to night-shift worker’s sleep quality, to maintain mental and physical health. These association need to be verified in prospective cohort studies.