Primulina rufipes Y.L. Su, P. Yang & Yan Liu (Gesneriaceae), a new species from Guangxi, China, is described and illustrated. Molecular phylogenetic analyses unambiguously put this species in Primulina. Morphological observations and comparisons showed that P. rufipes is similar to P. huaijiensis Z.L. Ning & J. Wang, differing by all over the plant densely pubescent and glandular-puberulent, leaf blade elliptic to rhomboid-ovate, and obliquely campanulate corolla without appendages. P. rufipes is also similar to P. yulinensis Ying Qin & Yan Liu and P. gongchengensis Y.S. Huang & Yan Liu in vegetative characters, but its obliquely campanulate corolla is obviously different from the latter two species.