目的：了解C型肝炎民眾對其疾病相關知識之特性及預測因子。
方法：以立意取樣調查137位C型肝炎成人民眾，採橫斷式、描述性研究設計。使用自填式結構性問卷收集資料，包含基本屬性量表及簡式C型肝炎知識量表，以描述性統計、獨立樣本t檢定、單因子變異數分析、皮爾森積差相關係數及逐步迴歸等統計方式分析資料。
結果：研究結果顯示C型肝炎民眾其C型肝炎知識程度平均得分為13.98±3.42分。答對最高的前三題為與C型肝炎者共用牙刷與刮鬍刀是安全的（96.35％）、使用新的（沒使用過的）針頭、針筒和用具能減少C型肝炎的傳染（95.62％）、人們可能在不知道已被感染情形下與C型肝炎共存許多年（93.43％）；答對率最差的三題分別為民國79年前接受輸血治療可能會被傳染C型肝炎（57.66％）、C型肝炎可能會經由性行為而感染（52.55％）、現在有C型肝炎疫苗能預防C型肝炎的傳染（31.39％）。收案於醫學中心、年紀較輕、已婚者、教育程度高中以上者及曾接受過口服抗病毒藥物及干擾素治療者，其C型肝炎相關知識得分顯著較高。C型肝炎相關知識的預測因子為高中職以下者（負向因子）及已婚者，可解釋21.4％的總變異量。
結論：本研究收案於醫學中心的民眾、越年輕者、已婚者、教育程度越高者、曾經接受過口服抗病毒藥物及干擾素治療者，其C型肝炎相關知識程度為高。利用C型肝炎知識量表，可做為C型肝炎知識測量之工具，並將其結果提供醫療從業人員對C型肝炎民眾C型肝炎知識程度之了解，建構預防觀念及衛教指導。

Purposes: To understand the characteristics and the predictors of disease-related knowledge among hepatitis C patients.
Methods: A cross-sectional, descriptive study design was adopted to survey 137 adults with hepatitis C using intentional sampling. Data were collected using a self-reported demographic/medical scale, and brief hepatitis C knowledge scale. Data were analyzed through descriptive statistics, independent sample t-tests, one-way analysis of variance, Pearson product-moment correlation coefficient, and stepwise regression.
Results: The mean score for hepatitis C knowledge among hepatitis C infected individuals was 13.98±3.42 score. The correct answers received most frequently were: it is unsafe to share toothbrushes and razors with people with hepatitis C (96.35%); using new (unused) needles, syringes, and utensils can reduce hepatitis C transmission (95.62%); and people can live with hepatitis C for many years without knowing they are infected (93.43%). The correct answers received least frequently were: it was possible to transmit hepatitis C through blood transfusions prior to 1990 (57.66%); hepatitis C can be transmitted through sexual intercourse (52.55%); and hepatitis C vaccine is now available to prevent transmission of hepatitis C (31.39%). Hepatitis C-related knowledge scores were significantly higher in participants whose surveys were collected by the Medical Center, younger infected participants, married individuals, participants with senior high school education or above, and participants who had received oral antiviral drugs and interferon therapy. Predictors of hepatitis C-related knowledge were having less than a senior high school education (negative factor), and being married. Together, these two factors explained 21.4% of the total variance.
Conclusions: Disease-related knowledge among hepatitis C patients may predict by individuals who have less than a senior high school education (negative effect), and individuals who are married. The hepatitis C knowledge scale can be used as a reliable tool to assess hepatitis C knowledge. It is advisable to enhance health education and guidance on hepatitis C transmission, and on vaccine availability and efficacy.