新冠病毒感染（COVID-19）自2019年底由中國武漢開始，很快蔓延成全世界傳染病，迄今在全球造成逾六億人口感染，超過650萬人喪生，全世界致死率為1.05%，堪稱本世紀最大的瘟疫，在人類健康與社會經濟上造成巨大損害。尤有甚者，眾多感染者在急性期後出現慢性延長的症狀，常見的有：咳嗽、頭痛、呼吸困難、腦霧、失眠、味覺障礙⋯等，這些變化多端的臨床表現雖不致命，但由於人數眾多，仍對大眾健康造成相當困擾。尤其是新冠病毒的突變株層出不窮，勢必有更多國人遭受感染而罹患長新冠症候群。因此有必要對感染者，即使是輕症病人，做持續的追蹤。此一新興傳染病造成的後遺症，仍有待更多的觀察與研究才能進一步瞭解，並提出最佳因應方案。本文根據最新的文獻，針對新冠病毒感染後症候群做系統性回顧，找出高危險因子，敘述其症狀表現與可能的致病機制，並提出可行的處理方式與預防之道，提供醫療人員在處置此類病人時的參考。

COVID-19 began in Wuhan, China at the end of 2019, and quickly spread into a worldwide infectious disease. So far, it has infected more than 600 million people worldwide and killed more than 6.5 million people. The global fatality rate is 1.05%. COVID-19 is the greatest plague of this century and has caused enormous damage to human health and socioeconomics. What's more, many infected people have chronic and prolonged symptoms after the acute phase. The common symptoms include cough, headache, dyspnea, brain fog, insomnia, dysgeusia, etc. Although these variable clinical manifestations are not fatal, due to the large number of people, it still poses considerable problems to public health. In particular, mutant strains of the new coronavirus are emerging one after another, and more people in the country are bound to be infected and suffer from long-COVID-19 syndrome. Therefore, it is necessary to keep track of infected people, even those with mild symptoms. The sequelae caused by this emerging infectious disease still need more observation and research to further understand and propose the best management for long-COVID-19 syndrome. Based on the latest literature, this article conducts a systematic review of longCOVID-19 syndrome, finds out high-risk factors, describes its symptoms and possible pathogenic mechanisms, and proposes feasible treatment methods and prevention methods to provide medical personnel with the best possible management for patients with long-COVID-19 syndrome.