緒論：本研究目的在透過系統性文獻回顧探討成人身體活動與新冠肺炎死亡風險之關係。方法：本研究搜尋英文及中文期刊論文電子資料庫(2020年1月至2022年8月)，且依據PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses)進行檢索。結果：共篩選出7篇有關成人身體活動與新冠肺炎死亡風險之期刊論文，其中包含3篇世代研究與4篇生態型研究。根據有限的證據，身體活動程度達到建議量者有較低的新冠肺炎死亡風險。此外，同時從事有氧運動與阻力運動的人則有更低的新冠肺炎死亡風險。擁有健康生活型態(含動態生活方式、飲食、睡眠、吸菸、飲酒等方面)的人在新冠肺炎死亡率上可進一步降低死亡風險。結語：成人從事身體活動可能具有降低新冠肺炎死亡風險之益處。本篇系統性文獻回顧的研究品質僅為「一般」到「佳」，未來仍有待具全國代表性樣本、設計良好、以及運用客觀儀器測量身體活動之大型世代研究，以提供更嚴謹的研究證據。

Introduction: The purpose of the study was to systematically review the past studies related to physical activity and the mortality risks of COVID-19 in adult populations. Methods: Major electronic databases in English and Chinese were searched from January 2020 to August 2022. The process of searching and screening for eligible studies was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Results: Seven eligible studies were identified, including three cohort studies and four ecological studies. Based on the limited evidence, it was found that individuals meeting the physical activity recommendations tend to have lower risks of COVID-19 mortality. People engaging in both aerobic and resistance exercises had additional risk reduction. Participants with a healthy lifestyle, including physically lifestyle, sleep, diet, smoking, and alcohol consumption, were more likely to have lower mortality due to COVID-19. Conclusion: Physical activity may provide benefits for decreasing the risks of COVID-19 mortality in adult populations. The research quality of the evidence is only graded as “fair to good.” More large-scale and well-designed cohort studies based on a nationally representative sample with device-based physical activity assessments are warranted.