樟芝(Antrodia camphorata)具有抗癌、保肝、降血壓、抗發炎、抗氧化等功效，功效成分包含三萜類(triterpenoids)、腺苷(adenosine)、多醣(polysaccharide)與β-1,3-葡聚醣(β-1,3-glucan)等。深層海水(Deep oceanwater, DOW)是位於海平面200公尺以下，含有豐富的礦物質與微量元素，可能做為關鍵酵素的輔因子，促進微生物生長或增加代謝產物。但DOW中的礦物質與微量元素多以無機形式存在，較不易於人體吸收。且過去研究未探討DOW對樟芝固態發酵與離子吸收之影響，因此本研究以不同濃度DOW為水份來源，進行液態及固態發酵，探討以DOW培養樟芝過程中功效成分生成及離子吸收之改變。結果顯示DOW可顯著提高樟芝固態發酵產物中三萜類含量，促進液態發酵中樟芝菌絲體生成量與提高腺苷與胞內β-1,3-葡聚醣含量。深層海水中的Mg²⁺吸收率為12至22%，而K⁺之吸收量於5倍之DOW時趨近飽和，最大吸收量為39.83 mg/L。表明樟芝生長及功效成份含量是受到被吸收之離子影響，此外DOW中被吸收之離子轉換為有機型態後，可能有益於離子被人體吸收。

Antrodia camphorata is proven to perform anticancer, anti-hepatotoxic, antihypertensive, anti-inflammatory, and anti-oxidative effects due to triterpenoids, adenosine, polysaccharides, and β-1,3- glucan. Deep ocean water (DOW) located 200 m or more deep sea level contains rich nutrients and minerals which can be used as cofactors for key enzymes to promote microbial growth or increase the biosynthesis of metabolites. However, DOW contains nutrients and minerals are inorganic forms not easy to be absorbed by human. The ions bio-absorption of A. camphorata from DOW in submerged culture and the effect of DOW on the growth of A. camphorata in solid culture are unclear. This study investigated the effect of DOW on the growth and ion bio-absorption of A. camphorata. Results showed that DOW raised the triterpenoids content of A. camphorata-fermented oat, as well as the adenosine and intracellular β-1,3-glucan content of submerged culture. The Mg²⁺ absorption rate was 12-22%. However, when the DOW concentration reached 5-fold, the K⁺ bio-absorption was not increased, the maximum of ion-absorption amount was 39.83 mg/L, indicating that the growth and functional components levels of A. camphorata were possible to be affected by the absorbed ions. Additionally, the absorbed DOW ions were transformed to organic ions, which could be benefit to the bio-availability in human.