肥胖是全球性的健康挑戰，因此及早發現病態性肥胖患者可能可以改善未來的不良後果。本次觀察性研究從2,050名醫院工作者中選出64位有病態性肥胖(身體質量指數≥35公斤/公尺2)的參與者及128位年齡和性別匹配的對照組進行分析。病態性肥胖的工作者有顯著較高的身體質量指數、體重、收縮壓、舒張壓、三酸甘油酯、空腹血糖、自我報告的平均每週工作時間和顯著較短的工作日平均睡眠時間(p值皆小於0.01)。病態性肥胖員工的主觀每週工時顯著地長於他們的客觀每週工時(p<0.001)以及對照組的主觀每週工時。在病態性肥胖組中，身體質量指數與客觀而非主觀的每週工時之間存在有顯著的正相關(p=0.028)。19位病態性肥胖女性員工中有7位患有多囊性卵巢症候群。在具備和缺乏減重動機的病態性肥胖參與者之間可以觀察到兩者體重變化存在明確差異(減少9.2±9.9公斤與增加1.5±8.0公斤)。這是第一個針對患有病態性肥胖醫院工作者的觀察性研究。我們的研究結果提供了個人意志影響病態性肥胖工作者體重的證據。期待機構管理者認真看待病態性肥胖產生的惡性循環。

Obesity is a global health challenge, and earlier detection of patients with morbid obesity may improve adverse outcomes. In this observational study, 64 participants with morbid obesity (body mass index ≥ 35 kg/m2) and 128 age- and sex-matched controls were selected from 2,050 hospital staff. A significantly higher body mass index, body weight, systolic blood pressure, diastolic blood pressure, triglyceride level, fasting plasma glucose level, self-reported average weekly working hours and a significantly shorter self-reported average sleep duration during weekdays were observed in the participants with morbid obesity (all p < 0.01). The subjective weekly working hours of these employees were significantly longer than their objective weekly working hours (p < 0.001) and the subjective weekly working hours of the healthy controls. Body mass index had a significant (p = 0.028) positive correlation with objective but not subjective weekly working hours in the group with morbid obesity. Seven of 19 women with morbid obesity had polycystic ovary syndrome. A definite difference in weight changes was observed between morbidly obese participants with and without motivation toward weight reduction (−9.2 ± 9.9 kg vs. 1.5 ± 8.0 kg). This is the first observational study that focused on hospital staff with morbid obesity. Our results provide evidence that personal volition affects body weight of morbidly obese employees, and a vicious cycle of morbid obesity should be taken seriously by the organization administrator.