皮膚鈣化（Calcinosis cutis）可以分成失養性（dystrophic）、代謝性（metastatic）、不明性及醫源性。失養性最常見，由局部組織損傷所致。當鈣化發生在胃黏膜時，則稱為胃黏膜鈣質沉積症（Gastric mucosal calcinosis, GMC），其包含3種亞型：失養性、代謝性和不明性，其中代謝性最常見，和鈣磷代謝異常有關。GMC發生率因研究族群而異，在胃鏡下通常呈現白色平坦斑塊或結節。高血磷可能導致高死亡率及心血管事件，因此當發現胃黏膜有鈣沉積時，應盡可能找出病因，並抽血確認鈣磷之數值以加以矯正。

Calcinosis cutis can be categorized into dystrophic, metastatic, idiopathic, and iatrogenic. Dystrophic calcification is the most common subtype and results from local tissue injury. When calcinosis cutis is noted over gastric mucosa, it is called gastric mucosal calcinosis (GMC). GMC has only three subtypes, including dystrophic, metastatic, and idiopathic. Metastatic subtype is the most common one. It is associated with abnormal calcium and phosphate metabolism. The incidence of GMC varies with the population being studied. GMC is usually demonstrated as white flat plaques or nodules by esophagogastroduodenoscopy. Hyperphosphatemia can lead to high mortality and cardiovascular event. Thus, when calcium deposition was found over gastric mucosa, we should look for possible etiologies and check laboratory data including calcium and phosphate.