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護理雜誌 MEDLINEScopus

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篇名 卵巢過度刺激徵候群
卷期 50:1
並列篇名 Ovarian Hyperstimulation Syndrome
作者 翁敏雪周弘傑詹景全李從業
頁次 98-102
關鍵字 卵巢過度刺激徵候群人工生殖科技管通透性第三腔室Ovarian hyperstimulation syndromeAssisted conceptionCapillary permeabilityThird spaceMEDLINEScopusTSCI
出刊日期 200302

中文摘要

     使用人工生殖科技懷孕易產生卵巢過度刺激徵候群,對強烈追求子賜的婦女而言,是很大的身心壓力。注射人類絨毛膜性腺激素後可能會使得血液中血管上皮因子的濃度上升,此因子會使血管通透性增加,血管內的液體跑至第三腔室,而造成卵巢過度刺激徵候群令人不適的徵狀。會產生卵巢過度刺激徵候群的危險因子包括:對人類絨毛膜性腺激素的敏感度、年紀、使用人類絨毛膜性腺激素做為驅動排卵者、體外受精次數、過敏史。雖然發生卵巢過度刺激徵候群並沒有比較好的治療方式,但是依病情程度的不同予以不同的治療,才能對症狀的緩解及減輕不適上有所助益。本文整合相關文獻資料,提供徵候群的概述並介紹治療方式,希望提昇臨床工作人員對此徵候群之了解,以做為日後護理照護之參考。

英文摘要

     Assisted conception in patients with ovarian hyperstimulation syndrome is a large stress. Serum vascular endothelial growth factor concentrationsrise in HCG administration. Vascular endothelial growth factor is an endothelial cell mitogen with angiogenic properties and is a mediator of ovarian hyperstimulation syndrome. The defect in ovarian hyperstimulation syndrome is altered capillary permeability, which results in increased capillary leakage of fluid into the third space. The risk factors associated with ovarian hyperstimulation syndrome are: a sensitive ovarian response to ovulation induction agents, the age of the patient, the administration of human chorionic gonadotrophin to trigger the ovulatory process, the frequency of assisted conception, patient's allergic history. The treatment is supportive, aiming at limiting and alleviating symptoms.

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