篇名 | Applying F-18 Fluorodeoxyglucose-PET/CT to Identify Ovarian Cancer in a Patient with Peritoneal Carcinomatosis from Unknown Primary Site |
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卷期 | 26:4 |
作者 | Lin, Mi-sheng 、 Shih, Chih-An 、 Peng, Nan-Jing 、 Hsu, Ping-I |
頁次 | 154-157 |
關鍵字 | computed tomography 、 peritoneal carcinomatosis 、 positron Emission Tomography {PET) |
出刊日期 | 201312 |
DOI | 10.3966/222696812013122604006 |
Searching for the primitive tumor of a peritoneal carcinomatosis is sometimes a difficult task even with modern diagnostic modalities. However, it is of paramount importance to identify primary tumors in patients with peritoneal carcinom.atosis, which are responsive to systemic chemotherapy and/or locoregional treatment. We presented a 74- years old female patient with massive malignant ascites. Abdominal computed tomography (CT) and Gallium scan failed to detect primary origin of peritoneal carcinomatosis. F-18 fluorodeoxyglucose (FDG) PET/CT showed a FDG-avid lesion in right ovary with multiple FDG-avid nodules over mesentery and retroperitoneum. Under the impression of right ovarian cancer with peritoneal seeding, she underwent cytoreductive surgery with total hysterectomy, bilateral salpingo-oophorectomy, bilateral pelvic lymph node, para-aortic lymph node dissection and partial omentectomy. Chemotherapy with avstin, taxol and carboplatin was administered following operation. The patient remained well after 4-month of follow-up. Her CA-125 and CA-199 went down and ascites resolved completely. Our data strongly suggest the combined F-18 FDG PET/CT is helpful in identifying primary tumor origin in some patients with peritoneal carcinomatosis, whose primary cancer cannot be detected by conventional diagnostic modalities.