身為設計專業人士，我們傾向以通用的方式應用某些設計原則和元素於計畫項目中。然而，如何確保人們能夠以相似的方式體驗和感知一個地方，使他們能夠從我們的設計中獲得同樣的利益，這是一個重要的議題。親生物設計旨在為人們的整體健康和福祉做出貢獻。本研究的主要的目的乃在評估來自兩個不同國家的受訪者在接觸親生物設計環境之前和之後的感知，以確定他們的感知差異。本研究透過以14種親生物設計模式為基礎的線上跨文化問卷調查，比較了墨西哥和台灣受訪者之間的主要差異。本硏究之有效樣本總數為222人，其中107位為墨西哥人和，115位為台灣人。結果顯示，兩國的受訪者對4種親生物設計模式的看法存在顯著差異。研究建議進一步探索和完善這些模式，以促進其未來的普遍應用。

As design professionals, we tend to apply certain design principles and elements in a universal way, assuming that the perception of each project by users from different part of the world might be the same. However，how to ensure that people can experience and perceive a place similarly in such a way that they can obtain equally benefits from our designs is an important issue. Concerning to biophilic design, which aims to contribute to the overall peopled health and well-being, this study is proposed with the aim of evaluating peopled perception from two different countries, before and after being exposed to a biophilic design environment, in order to identify their perceptual differences. In this research, authors compare the main differences between Mexican and Taiwanese respondents through a cross-cultural study conducted by an online survey based on the 14 patterns of biophilic design. The total valid sample was 222, 107 Mexican and 115 Taiwanese. The results revealed significant differences in the perception of the participants from the two countries regarding 4 biophilic design patterns, suggesting further exploration and refinement of the patterns to contribute to their future universal application.