在毛細管電泳數值模型中，一般常用來計算溶質在毛細管電泳晶片中的流動，通常使用濃度方程式。但濃度方程式並不能清楚地描述不同帶電性質溶質離子之運動現象。本研究使用複合PIC法以描述不同電性之溶質離子在毛細電泳內運動的情形。以此方法可以更清楚地了解不同電性之溶質離子在毛細管電泳中運動之現象，以期對毛細電泳晶片之設計有所裨益。

Traditional numerical schemes use the concentration diffusion equation to simulate the solute concentration distribution in CZE (capillary zone electrophoresis) systems. However, although this equation adequately describes the diffusion of a solute liquid in such systems, it cannot describe the different motions of the differently charged solute ions. Therefore, this study employs a particle model to simulate solute ionic migration. Using the Navier-Stokes equation and the PIC (particle in caell) method, this study examines the absolute mobility of negatively and positively charged ions in non-aqueous solvents in a CZE system. The results show that the zeta potential on the channel wall affects the migration of the positive and negative ions in the electrical double layer (EDL) in different ways. Specifically, the positive ions accumulate at the channel wall, while the negative ions are pushed out of the EDL. Furthermore, it is shown that the positive ions migrate more rapidly than the negative ions in the injection process.