本研究以白老鼠為受試對象，旨在探討七天吊尾的不活動與每天每公斤體重20毫克的維他命E補給對骨骷肌的重量與過氧化物歧化鵲、穀耽甘肽過氧化酶、穀耽甘肽還原梅等抗氧化酷的影響。四十隻白老鼠以隨機分配方式每十隻分配至下各組:(1)不活動一維生素E補給組;(2)不活動組; (3)維生素E補給 組;(4)控制缸。採周二因子變異數分析考驗不活動與維生素E補給對比目魚肌的重量典過氧化物歧化梅、穀就甘且太過氧化酶、穀胱甘肽還原鵬等抗氧化峙的差異情形。結果顯示不活動組的比目魚肌重量顯著地少於(26.46%)正常活動組的比目魚肌重量;在另一方面，維生素E的補給對比目魚吵肌的重量並沒有造成差異。對於抗氧化臨的影響，結泉指出不活動與維生素E補給對於過氧化物歧化峙、穀胱甘肽過氧化酶、穀耽甘服還原悔沒有產生顯著性的差異。上述的發現印證了七天吊尾的不活動能夠引起骨酪肌的肌肉委縮。而不活動或者維生素E補給是在低耗氧量的狀況下，因此沒有產生太多的過氧化物，也就不會促使抗氧化峙的提升。

Using a rat model， the effects of 7 days' immobilization induced by tail-cast suspension and vitamin E supplementation(20mg/kg/d) on tissue weight(mg) and antioxidant enzymes(U/mg protein) Superoxide dismutase(SOD)， glutathione peroxidase(GPx) and glutathione reductase(GRd) in the skeletal muscle were studied. Forty Sprague-Dawley rats were grouped as follows: l)immobilization-vitaminE supplementation; 2)immobilization; 3)vitamin E supplementation; 4)control;(10 per group). Two way ANOVA was performed to examine the effects of immobilization and vitamin E supplementation on soleus muscle weight， SOD， GPx， and GRd. The soleus muscle weight in the immobilization group was signifcantly lower(22.46%) than that in the control group; in contrast， vitamin E supplementation did not alter the soleus muscle weight. Furthermore， the immobilization and/or vitamin E supplementation had no effect on SOD， GPx， and GRd in the soleus. The findings indicate that the immobilization induced by tail-cast suspension for 7 days could result in skeletal muscle atrophy. Itis concluded that immobilization and/or vitamin E supplementation may not promote increases in antioxidant enzymes due to less oxygen consumption during immobilization which decreases superoxide production.